Thyroid nodules proven to be benign with several biopsies which are over 2 cm and not below the clavicle. All nodules studied with ultrasound should have a benign appearance, and all prominent nodules present should be individually biopsied. Nodules should not be larger than 80 ml
Larger nodules become more symptomatic as they push against the esophagus and trachea. This may cause difficulty with breathing and swallowing. Additionally, nodules producing excessive thyroid hormone cause many other symptoms and health problems.
Patients who have large nodules (over 2 cm) which have been identified by CT scan or ultrasound and who have symptoms of compression. One or many individual ultrasound guided FNA biopsies of the nodules are necessary. These biopsies must demonstrate benign pathology.